Getting back to the beginning of how we started this podcast, it was just Austin and myself covering our entire supplement intake that consists of clinically backed and research health and ergogenic bodybuilding supplements. We could have gone on and on but covered just about everything in this one! Below is some of the literature referenced within the episode (for those that enjoy to take the education process one step forward.)
NAC
1. Therapeutic efficacy of aortic administration of N-acetylcysteine as a chemoprotectant against bone marrow toxicity after intracarotid administration of alkylators, with or without glutathione depletion in a rat model. E. A. Neuwelt, M. A. Pagel, B. P. Hasler, T. G. Deloughery, L. L. Muldoon. Cancer Res. 2001 (https://www.ncbi.nlm.nih.gov/pubmed/11691805)
2. N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action. Olivia Dean, Frank Giorlando, Michael Berk. J Psychiatry Neurosci. 2011 (https://www.ncbi.nlm.nih.gov/pubmed/21118657)
3. Assessment of glutathione homeostasis. Gennaro Giordano, Collin C. White, Lucio G. Costa
Methods Mol Biol. 2011 (https://www.ncbi.nlm.nih.gov/pubmed/21815068)
4. Glutathione pathways in the brain. Ralf Dringen, Johannes Hirrlinger. Biol Chem. 2003 (https://www.ncbi.nlm.nih.gov/pubmed/12751781)
5. N-Acetylcysteine's attenuation of fatigue after repeated bouts of intermittent exercise: practical implications for tournament situations. James N. Cobley, Chris McGlory, James P. Morton, Graeme L. Close. Int J Sport Nutr Exerc Metab. 2011 (https://www.ncbi.nlm.nih.gov/pubmed/22089305)
6. N-acetylcysteine inhibits muscle fatigue in humans. Reid, M. B., Stokić, D. S., Koch, S. M., Khawli, F. A., & Leis, A. A. Journal of Clinical Investigation. 1994 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC330079/)
7 .Acetaminophen poisoning: a case report of the use of acetylcysteine. R. D. Scalley, C. S. Conner. Am J Hosp Pharm. 1978 (https://www.ncbi.nlm.nih.gov/pubmed/677146)
8. A dual effect of N-acetylcysteine on acute ethanol-induced liver damage in mice.
An-Lian Wang, Jian-Ping Wang, Hua Wang, Yuan-Hua Chen, Lei Zhao, Long-Shou Wang, Wei Wei, De-Xiang Xu. Hepatol Res. 2006 (https://www.ncbi.nlm.nih.gov/pubmed/16439183)
9. The administration of N-acetylcysteine reduces oxidative stress and regulates glutathione metabolism in the blood cells of workers exposed to lead.. Sławomir Kasperczyk, Michał Dobrakowski, Aleksandra Kasperczyk, Alina Ostałowska, Ewa Birkner. Clin Toxicol (Phila) 2013 (https://www.ncbi.nlm.nih.gov/pubmed/23731375)
Agmatine
References
1. Hemodynamic and vascular response to resistance exercise with L-arginine.
Christopher A. Fahs, Kevin S. Heffernan, Bo Fernhall. Med Sci Sports Exerc. 2009 (https://www.ncbi.nlm.nih.gov/pubmed/19276857)
2. Bolus arginine supplementation affects neither muscle blood flow nor muscle protein synthesis in young men at rest or after resistance exercise. Jason E. Tang, Paul J. Lysecki, Joshua J. Manolakos, Maureen J. MacDonald, Mark A. Tarnopolsky, Stuart M. Phillips. J Nutr. 2011 (https://www.ncbi.nlm.nih.gov/pubmed/21191143)
3. Inhibition of purified nitric oxide synthase from rat cerebellum and macrophage by L-arginine analogs.Y. Komori, G. C. Wallace, J. M. Fukuto. Arch Biochem Biophys. 1994 (https://www.ncbi.nlm.nih.gov/pubmed/7527206)
4. Metabolism of agmatine (clonidine-displacing substance) by diamine oxidase and the possible implications for studies of imidazoline receptors. A. Holt, G. B. Baker. Prog Brain Res. 1995 (https://www.ncbi.nlm.nih.gov/pubmed/8584654)
5. A new crystal form of human diamine oxidase. Aaron P. McGrath, Kimberly M. Hilmer, Charles A. Collyer, David M. Dooley, J. Mitchell Guss. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Feb 1 (https://www.ncbi.nlm.nih.gov/pubmed/20124708)
6. Transport and metabolism of agmatine in rat hepatocyte cultures. C. Cabella, G. Gardini, D. Corpillo, G. Testore, S. Bedino, S. P. Solinas, C. Cravanzola, C. Vargiu, M. A. Grillo, S. Colombatto. Eur J Biochem. 2001 Feb (https://www.ncbi.nlm.nih.gov/pubmed/11179960)
7. Exposure of rat isolated stomach and rats in vivo to [(14)C]agmatine: accumulation in the stomach wall and distribution in various tissues. Gerhard J. Molderings, Anja Heinen, Sigrid Menzel, Manfred Göthert. Fundam Clin Pharmacol. 2002 Jun (https://www.ncbi.nlm.nih.gov/pubmed/12165069)
8. The clinical antidepressant effect of exogenous agmatine is not reversed by parachlorophenylalanine: a pilot study. Baron Shopsin. Acta Neuropsychiatr. 2013 Apr (https://www.ncbi.nlm.nih.gov/pubmed/25287313)
9. Long-term (5 years), high daily dosage of dietary agmatine--evidence of safety: a case report.
Gad M. Gilad, Varda H. Gilad. J Med Food. 2014 Nov (https://www.ncbi.nlm.nih.gov/pubmed/25247837)
10. Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury. Fairbanks, C. A., Schreiber, K. L., Brewer, K. L., Yu, C.-G., Stone, L. S., Kitto, K. F., Wilcox, G. L. Proceedings of the National Academy of Sciences of the United States of America (2000) (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC27068/)
Highly Branched Cyclic Dextrin (HBCD)
References
2. A sports drink based on highly branched cyclic dextrin generates few gastrointestinal disorders in untrained men during bicycle exercise. Takii, H., Kometani, T., Nishimura, T., Kuriki, T., and Fushiki, T. Food Sci. Technol. Res. 2004 (https://www.jstage.jst.go.jp/article/fstr/10/4/10_4_428/_article)
3. Fluids containing a highly branched cyclic dextrin influence
the gastric emptying rate. Takii, H., Takii Nagao, Y., Kometani, T., Nishimura, T., Nakae, T., Kuriki, T., and Fushiki, T. Int. J. Sports Med. 2005 (https://www.ncbi.nlm.nih.gov/pubmed/15900642)
4. Factors limiting gastric emptying during rest and exercise. Costill, D.L. and Saltin, B. J. Appl. Physiol. 1974 (http://jap.physiology.org/content/37/5/679)
5. The pattern of emptying of the human stomach. J. N. Hunt, W. R. Spurrell. J Physiol. 1951 (https://www.ncbi.nlm.nih.gov/pubmed/14832765)
6. Evaluation of Exercise Performance with the Intake of Highly Branched Cyclic Dextrin in Athletes. Shiraki, T., Kometani T., Yoshitani, K., Takata H., Nomura T. Food Science and Technology Research. 2015 (https://www.jstage.jst.go.jp/article/fstr/21/3/21_499/_html#bib3)
Vitamins C & D
1. Effect of vitamin C supplementation on postprandial oxidative stress and lipid profile in type 2 diabetic patients. Zohreh Mazloom, Najmeh Hejazi, Mohammad-Hossein Dabbaghmanesh, Hamid-Reza Tabatabaei, Afsane Ahmadi, Hasti Ansar. Pak J Biol Sci. 2011 Oct 1; 14(19): 900–904.
2. Ascorbic acid protects neurons from injury induced by glutamate and NMDA. M. D. Majewska, J. A. Bell. Neuroreport. 1990 Nov-Dec; 1(3-4): 194–196.
3. High-dose ascorbic acid increases intercourse frequency and improves mood: a randomized controlled clinical trial. Stuart Brody. Biol Psychiatry. 2002 Aug 15; 52(4): 371–374.
4. Ascorbic acid prevents vascular dysfunction induced by oral glucose load in healthy subjects. Sergio De Marchi, Manlio Prior, Anna Rigoni, Sara Zecchetto, Fanny Rulfo, Enrico Arosio. Eur J Intern Med. 2012 Jan; 23(1): 54–57. Published online 2011 Aug 27. doi: 10.1016/j.ejim.2011.07.019
5. The effect of 2 weeks vitamin C supplementation on immunoendocrine responses to 2.5 h cycling exercise in man. Glen Davison, Michael Gleeson. Eur J Appl Physiol. 2006 Jul; 97(4): 454–461. Published online 2006 May 10. doi: 10.1007/s00421-006-0196-7
6. No effect of antioxidant supplementation on muscle performance and blood redox status adaptations to eccentric training. Anastasios A. Theodorou, Michalis G. Nikolaidis, Vassilis Paschalis, Stilianos Koutsias, George Panayiotou, Ioannis G. Fatouros, Yiannis Koutedakis, Athanasios Z. Jamurtas. Am J Clin Nutr. 2011 Jun; 93(6): 1373–1383. Published online 2011 Apr 20. doi: 10.3945/ajcn.110.009266
7. Vitamin C provision improves mood in acutely hospitalized patients. Michelle Zhang, Line Robitaille, Shaun Eintracht, L. John Hoffer. Nutrition. 2011 May; 27(5): 530–533. Published online 2010 Aug 5. doi: 10.1016/j.nut.2010.05.016
8. Influence of acute vitamin C and/or carbohydrate ingestion on hormonal, cytokine, and immune responses to prolonged exercise. Glen Davison, Michael Gleeson. Int J Sport Nutr Exerc Metab. 2005 Oct; 15(5): 465–479.
9. Influence of vitamin C supplementation on oxidative and immune changes after an ultramarathon. David C. Nieman, Dru A. Henson, Steve R. McAnulty, Lisa McAnulty, Nathaniel S. Swick, Alan C. Utter, Debra M. Vinci, Shannon J. Opiela, Jason D. Morrow. J Appl Physiol (1985) 2002 May; 92(5): 1970–1977. doi: 10.1152/japplphysiol.00961.2001
10. Independent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality. Harald Dobnig, Stefan Pilz, Hubert Scharnagl, Wilfried Renner, Ursula Seelhorst, Britta Wellnitz, Jürgen Kinkeldei, Bernhard O. Boehm, Gisela Weihrauch, Winfried Maerz. Arch Intern Med. 2008 Jun 23; 168(12): 1340–1349. doi: 10.1001/archinte.168.12.1340
11. Effect of vitamin D on blood pressure: a systematic review and meta-analysis. Miles D. Witham, M. Adnan Nadir, Allan D. Struthers. J Hypertens. 2009 Oct; 27(10): 1948–1954. doi: 10.1097/HJH.0b013e32832f075b
12. A 12-week double-blind randomized clinical trial of vitamin D3 supplementation on body fat mass in healthy overweight and obese women. Amin Salehpour, Farhad Hosseinpanah, Farzad Shidfar, Mohammadreza Vafa, Maryam Razaghi, Sahar Dehghani, Anahita Hoshiarrad, Mahmoodreza Gohari. Nutr J. 2012; 11: 78. Published online 2012 Sep 22. doi: 10.1186/1475-2891-11-78
13. Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren. Mitsuyoshi Urashima, Takaaki Segawa, Minoru Okazaki, Mana Kurihara, Yasuyuki Wada, Hiroyuki Ida. Am J Clin Nutr. 2010 May; 91(5): 1255–1260. Published online 2010 Mar 10. doi: 10.3945/ajcn.2009.29094
14. Impact of vitamin D supplementation during a resistance training intervention on body composition, muscle function, and glucose tolerance in overweight and obese adults. Andres E. Carrillo, Michael G. Flynn, Catherine Pinkston, Melissa M. Markofski, Yan Jiang, Shawn S. Donkin, Dorothy Teegarden. Clin Nutr. Author manuscript; available in PMC 2015 Mar 19. Published in final edited form as: Clin Nutr. 2013 Jun; 32(3): 375–381. Published online 2012 Aug 31. doi: 10.1016/j.clnu.2012.08.014
15. Effect of vitamin D supplementation on testosterone levels in men.
S. Pilz, S. Frisch, H. Koertke, J. Kuhn, J. Dreier, B. Obermayer-Pietsch, E. Wehr, A. Zittermann. Horm Metab Res. 2011 Mar; 43(3): 223–225. Published online 2010 Dec 10. doi: 10.1055/s-0030-1269854
16. A systems-based investigation into vitamin D and skeletal muscle repair, regeneration, and hypertrophy. Owens DJ, Sharples AP, Polydorou I, Alwan N, Donovan T, Tang J, Fraser WD, Cooper RG, Morton JP, Stewart C, Close GL. Am J Physiol Endocrinol Metab. 2015 Dec 15;309(12):E1019-31. doi: 10.1152/ajpendo.00375.2015.
Ashwagandha
1. Selective Killing of Cancer Cells by Ashwagandha Leaf Extract and Its Component Withanone Involves ROS Signaling. Nashi Widodo, Didik Priyandoko, Navjot Shah, Renu Wadhwa, Sunil C. Kaul. PLoS One. 2010; 5(10): e13536. Published online 2010 Oct (https://www.ncbi.nlm.nih.gov/pubmed/20975835)
2. Adaptogenic and cardioprotective action of ashwagandha in rats and frogs.
J. N. Dhuley. J Ethnopharmacol. 2000 Apr (https://www.ncbi.nlm.nih.gov/pubmed/10720789)
3. Exploratory study to evaluate tolerability, safety, and activity of Ashwagandha (Withania somnifera) in healthy volunteers. Ashwinikumar A. Raut, Nirmala N. Rege, Firoz M. Tadvi, Punita V. Solanki, Kirti R. Kene, Sudatta G. Shirolkar, Shefali N. Pandey, Rama A. Vaidya, Ashok B. Vaidya. J Ayurveda Integr Med. 2012 Jul-Sep (https://www.ncbi.nlm.nih.gov/pubmed/23125505)
4. The proteasome inhibitor bortezomib affects osteoblast differentiation in vitro and in vivo in multiple myeloma patients. Nicola Giuliani, Francesca Morandi, Sara Tagliaferri, Mirca Lazzaretti, Sabrina Bonomini, Monica Crugnola, Cristina Mancini, Eugenia Martella, Luca Ferrari, Antonio Tabilio, Vittorio Rizzoli. Blood. 2007 Jul 1; 110(1): 334–338. Published online 2007 Mar (https://www.ncbi.nlm.nih.gov/pubmed/17371942)
5. A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. K. Chandrasekhar, Jyoti Kapoor, Sridhar Anishetty. Indian J Psychol Med. 2012 Jul-Sep (https://www.ncbi.nlm.nih.gov/pubmed/23439798)
6. Withania somnifera root extract in the regulation of lead-induced oxidative damage in male mouse. S. S. Chaurasia, S. Panda, A. Kar. Pharmacol Res. 2000 Jun (https://www.ncbi.nlm.nih.gov/pubmed/10816336)
7. Search for natural products related to regeneration of the neuronal network.
Chihiro Tohda, Tomoharu Kuboyama, Katsuko Komatsu. Neurosignals. 2005 (https://www.ncbi.nlm.nih.gov/pubmed/15956813)
8. Neuritic regeneration and synaptic reconstruction induced by withanolide A
Tomoharu Kuboyama, Chihiro Tohda, Katsuko Komatsu. Br J Pharmacol. 2005 Apr (https://www.ncbi.nlm.nih.gov/pubmed/15711595)
9. Withania somnifera improves semen quality by regulating reproductive hormone levels and oxidative stress in seminal plasma of infertile males. Mohammad Kaleem Ahmad, Abbas Ali Mahdi, Kamla Kant Shukla, Najmul Islam, Singh Rajender, Dama Madhukar, Satya Narain Shankhwar, Sohail Ahmad. Fertil Steril. 2010 Aug; 94(3): 989–996. Published online 2009 Jun (https://www.ncbi.nlm.nih.gov/pubmed/19501822)
Krill Oil
Grape Seed Extract & Taurine
1. Effect of grape seed extract on blood pressure in subjects with the metabolic syndrome.
Brahmesh Sivaprakasapillai, Indika Edirisinghe, Jody Randolph, Francene Steinberg, Tissa Kappagoda. Metabolism. 2009 Dec; 58(12): 1743–1746. Published online 2009 Jul 15. doi: 10.1016/j.metabol.2009.05.030
2. The effect of grape seed extract on cardiovascular risk markers: a meta-analysis of randomized controlled trials. Harm H. H. Feringa, Dayne A. Laskey, Justine E. Dickson, Craig I. Coleman
J Am Diet Assoc. 2011 Aug; 111(8): 1173–1181. doi: 10.1016/j.jada.2011.05.015
3. Grape seed and red wine polyphenol extracts inhibit cellular cholesterol uptake, cell proliferation, and 5-lipoxygenase activity. Wayne R. Leifert, Mahinda Y. Abeywardena. Nutr Res. 2008 Dec; 28(12): 842–850. Published online 2008 Nov 8. doi: 10.1016/j.nutres.2008.09.001
4. Effects of grape seed extract in Type 2 diabetic subjects at high cardiovascular risk: a double blind randomized placebo controlled trial examining metabolic markers, vascular tone, inflammation, oxidative stress and insulin sensitivity. P. Kar, D. Laight, H. K. Rooprai, K. M. Shaw, M. Cummings. Diabet Med. 2009 May; 26(5): 526–531. doi: 10.1111/j.1464-5491.2009.02727.x
5. Effect of a standardized grape seed extract on low-density lipoprotein susceptibility to oxidation in heavy smokers. Giovanni B. Vigna, Fabrizio Costantini, Giancarlo Aldini, Marina Carini, Alberico Catapano, Fabio Schena, Arianna Tangerini, Rosanna Zanca, Egidio Bombardelli, Paolo Morazzoni, et al. Metabolism. 2003 Oct; 52(10): 1250–1257.
6. Specialty Supplements and Prostate Cancer Risk in the VITamins And Lifestyle (VITAL) Cohort. Theodore M. Brasky, Alan R. Kristal, Sandi L. Navarro, Johanna W. Lampe, Ruth E. Patterson, Ulrike Peters, Emily White. Nutr Cancer. Author manuscript; available in PMC 2012 May 1. Published in final edited form as: Nutr Cancer. 2011 May; 63(4): 573–582. doi: 10.1080/01635581.2011.553022
7. Effect of taurine supplementation on exercise capacity of patients with heart failure.
Mohamad Reza Beyranvand, Mahshid Kadkhodai Khalafi, Valiollah Dabidi Roshan, Sirrus Choobineh, Saeid Alipour Parsa, Mohammad Asadpour Piranfar. J Cardiol. 2011 May; 57(3): 333–337. Published online 2011 Feb 19. doi: 10.1016/j.jjcc.2011.01.007
8. The effect of acute taurine ingestion on endurance performance and metabolism in well-trained cyclists. Jane A. Rutherford, Lawrence L. Spriet, Trent Stellingwerff. Int J Sport Nutr Exerc Metab. 2010 Aug; 20(4): 322–329.
9. Effect of taurine supplementation on exercise capacity of patients with heart failure.
Mohamad Reza Beyranvand, Mahshid Kadkhodai Khalafi, Valiollah Dabidi Roshan, Sirrus Choobineh, Saeid Alipour Parsa, Mohammad Asadpour Piranfar. J Cardiol. 2011 May; 57(3): 333–337. Published online 2011 Feb 19. doi: 10.1016/j.jjcc.2011.01.007
10. Two weeks taurine supplementation reverses endothelial dysfunction in young male type 1 diabetics. Michael A. Moloney, Rowan G. Casey, David H. O'Donnell, Patricia Fitzgerald, Chris Thompson, David J. Bouchier-Hayes. Diab Vasc Dis Res. 2010 Oct; 7(4): 300–310. Published online 2010 Jul 28. doi: 10.1177/1479164110375971
11. The taurine transporter gene and its role in renal development. X. Han, A. M. Budreau, R. W. Chesney. Amino Acids. 2000; 19(3-4): 499–507.
12. Localization of the membrane defect in transepithelial transport of taurine by parallel studies in vivo and in vitro in hypertaurinuric mice. R W Chesney, C R Scriver, F Mohyuddin
J Clin Invest. 1976 Jan; 57(1): 183–193.
13. Adaptive regulation of taurine transport in two continuous renal epithelial cell lines.
D. P. Jones, L. A. Miller, R. W. Chesney. Kidney Int. 1990 Aug; 38(2): 219–226.
14. Perinatal Taurine Alters Arterial Pressure Control and Renal Function in Adult Offspring
Sanya Roysommuti, Wichaporn Lerdweeraphon, Pisamai Malila, Dusit Jirakulsomchok, J. Michael Wyss. Adv Exp Med Biol. Author manuscript; available in PMC 2010 Jan 1.
Published in final edited form as: Adv Exp Med Biol. 2009; 643: 145–156.
15. Perinatal taurine depletion increases susceptibility to adult sugar-induced hypertension in rats
Sanya Roysommuti, Atchariya Suwanich, Dusit Jirakulsomchok, J. Michael Wyss
Adv Exp Med Biol. Author manuscript; available in PMC 2010 Jan 1. Published in final edited form as: Adv Exp Med Biol. 2009; 643: 123–133. doi: 10.1007/978-0-387-75681-3_13
Milk Thistle
1. Biochemical effects of the flavonolignane silibinin on RNA, protein and DNA synthesis in rat livers. J. Sonnenbichler, I. Zetl. Prog Clin Biol Res. 1986 (https://www.ncbi.nlm.nih.gov/pubmed/2424029)
2. Milk thistle in liver diseases: past, present, future. Ludovico Abenavoli, Raffaele Capasso, Natasa Milic, Francesco Capasso. Phytother Res. 2010 (https://www.ncbi.nlm.nih.gov/pubmed/20564545)
3. Free radicals in tissue damage in liver diseases and therapeutic approach. J. Fehér, I. Láng, G. Deák, A. Cornides, K. Nékám, P. Gergely. Tokai J Exp Clin Med. 1986 (https://www.ncbi.nlm.nih.gov/pubmed/3452238)
4. Silymarin attenuated the amyloid β plaque burden and improved behavioral abnormalities in an Alzheimer's disease mouse model. Nakaba Murata, Kazuma Murakami, Yusuke Ozawa, Noriaki Kinoshita, Kazuhiro Irie, Takuji Shirasawa, Takahiko Shimizu. Biosci Biotechnol Biochem. 2010; 74(11): 2299–2306. Published online 2010 (https://www.ncbi.nlm.nih.gov/pubmed/21071836)
5. The efficacy of Silybum marianum (L.) Gaertn. (silymarin) in the treatment of type II diabetes: a randomized, double-blind, placebo-controlled, clinical trial. H. Fallah Huseini, B. Larijani, R. Heshmat, H. Fakhrzadeh, B. Radjabipour, T. Toliat, Mohsin Raza. Phytother Res. 2006 (https://www.ncbi.nlm.nih.gov/pubmed/17072885)
6. Advances in the use of milk thistle (Silybum marianum). Janice Post-White, Elena J. Ladas, Kara M. Kelly. Integr Cancer Ther. 2007 (https://www.ncbi.nlm.nih.gov/pubmed/17548789)
EGCG
Curcumin
1. Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer. R. A. Sharma, H. R. McLelland, K. A. Hill, C. R. Ireson, S. A. Euden, M. M. Manson, M. Pirmohamed, L. J. Marnett, A. J. Gescher, W. P. Steward. Clin Cancer Res. 2001 (https://www.ncbi.nlm.nih.gov/pubmed/11448902)
2. Dose escalation of a curcuminoid formulation. Christopher D Lao, Mack T Ruffin, IV, Daniel Normolle, Dennis D Heath, Sandra I Murray, Joanne M Bailey, Martha E Boggs, James Crowell, Cheryl L Rock, Dean E Brenner. BMC Complement Altern Med. 2006 (https://www.ncbi.nlm.nih.gov/pubmed/16545122)
3. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. G. Shoba, D. Joy, T. Joseph, M. Majeed, R. Rajendran, P. S. Srinivas. Planta Med. 1998 (https://www.ncbi.nlm.nih.gov/pubmed/9619120)
4. Insulin resistance associated to obesity: the link TNF-alpha. Iria Nieto-Vazquez, Sonia Fernández-Veledo, David K. Krämer, Rocio Vila-Bedmar, Lucia Garcia-Guerra, Margarita Lorenzo. Arch Physiol Biochem. 2008 (https://www.ncbi.nlm.nih.gov/pubmed/18629684)
5. The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. Kern, P. A., Saghizadeh, M., Ong, J. M., Bosch, R. J., Deem, R., & Simsolo, R. B. (1995). Journal of Clinical Investigation (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC295809/)
6. Oral supplementation of turmeric decreases proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis: a randomized and placebo-controlled study. Parviz Khajehdehi, Batol Zanjaninejad, Elham Aflaki, Mohamadali Nazarinia, Fariborz Azad, Leila Malekmakan, Gholam-Reza Dehghanzadeh. J Ren Nutr. 2012 (https://www.ncbi.nlm.nih.gov/pubmed/21742514)
7. Screening of potential cancer preventing chemicals as aromatase inhibitors in an in vitro assay.
E. L. White, L. J. Ross, V. E. Steele, G. J. Kelloff, D. L. Hill. Anticancer Res. 1999 (https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/10368648/citedby/?tool=pubmed)
8. Reference profile correlation reveals estrogen-like trancriptional activity of Curcumin.
Beatrice E. Bachmeier, Valentina Mirisola, Francesco Romeo, Luca Generoso, Alessia Esposito, Raffaella Dell'eva, Fabiola Blengio, Peter H. Killian, Adriana Albini, Ulrich Pfeffer. Cell Physiol Biochem. 2010 (https://www.ncbi.nlm.nih.gov/pubmed/20798532)
9. Effects of dietary curcumin on glutathione S-transferase and malondialdehyde-DNA adducts in rat liver and colon mucosa: relationship with drug levels. R. A. Sharma, C. R. Ireson, R. D. Verschoyle, K. A. Hill, M. L. Williams, C. Leuratti, M. M. Manson, L. J. Marnett, W. P. Steward, A. Gescher. Clin Cancer Res. 2001 (https://www.ncbi.nlm.nih.gov/pubmed/11350917)
Tyrosine
Citrus Bergamont
Boswellia Serrata
LEARN MORE ABOUT THE HOSTS
ABOUT ALEX KIKEL, Prep Coach
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Yet another fun time sitting down with Austin Stout and fellow ProjectAD brother IFBB PRO Sasan Heirati! We talked about everything from Sasan's beginnings, previous preps, current prep, working with Chris Aceto, and his overall approach to training, nutrition, and supplementation! Follow Sasan and watch him do DAMAGE on the Pro Stage in just under 10 weeks!
https://www.facebook.com/sasan.heirati
https://www.instagram.com/sas_heirati/?hl=en
https://twitter.com/sas_heirati?lang=en
LEARN MORE ABOUT THE HOSTS
ABOUT ALEX KIKEL, Prep Coach
MS, PES, NASM CPT, NASE Speed and Explosion Specialist lvl II
Owner of The Prep Coach: Online Prep Coaching Service (www.theprepcoach.com)
http://www.facebook.com/alex.kikel.9
Workout Log: http://forum.bodybuilding.com/showthread.php?t=168793973
Instagram: alex_kikel
Email: alex@theprepcoach.com
Amateur Bodybuilder & RAW Powerlifter
ABOUT AUSTIN STOUT, Prep Coach
Founder and CEO of Integrated Muscle and Health
Gym Owner
B.S. Nutrition Science
CPT
Certified Strength and Conditioning Coach
Facebook: Austin.stout.12
IG: Austinst8
•••SUPPORT OUR SPONSOR•••
(SUPPLEMENTS) www.projectad.me___use discount code “BFR25” for 25% off your order!
(SITE ENHANCEMENT OIL) www.mediphorm.com___use discount code “BFR” for 10% off your order!
•••FIND THE EPISODES•••
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www.youtube.com/user/NaturallyGreatBB
http://beastfitnessradio.libsyn.com
During the introduction, Austin and myself discussed what happened at the Arnold Classic, our thoughts, and Essential Supplements on a Budget. Then in the second half of the show, we had on bodybuilder Jeff Black and discussing Bodybuilding with A Chronic Disease. In his case, its Osteogenesis Imperfect (also known as brittle bones disease.) This is one of the most inspiring and motivating stories I have yet to hear within bodybuilding! Follow Jeff Black on FaceBook and Instagram and expect him to launch his YouTube channel within the following weeks!
LEARN MORE ABOUT THE HOSTS
ABOUT ALEX KIKEL, Prep Coach
MS, PES, NASM CPT, NASE Speed and Explosion Specialist lvl II
Owner of The Prep Coach: Online Prep Coaching Service (www.theprepcoach.com)
http://www.facebook.com/alex.kikel.9
Workout Log: http://forum.bodybuilding.com/showthread.php?t=168793973
Instagram: alex_kikel
Email: alex@theprepcoach.com
Amateur Bodybuilder & RAW Powerlifter
ABOUT AUSTIN STOUT, Prep Coach
Founder and CEO of Integrated Muscle and Health
Gym Owner
B.S. Nutrition Science
CPT
Certified Strength and Conditioning Coach
Facebook: Austin.stout.12
IG: Austinst8
•••SUPPORT OUR SPONSOR•••
(SITE ENHANCEMENT OIL) www.mediphorm.com___use discount code “BFR” for 10% off your order!
(SUPPLEMENTS) www.projectad.me___use discount code “BFR25” for 25% off your order!
•••FIND THE EPISODES•••
https://itunes.apple.com/us/podcast/beastfitness-radios-podcast/id1065532968
www.youtube.com/user/NaturallyGreatBB
http://beastfitnessradio.libsyn.com
As always I feel honored to be able to talk with my co-host Austin Stout and our guest for this show, Dr. Eric Trexler. Eric is a PhD student at UNC Chapel Hill and holds an MA, CSCS, CISSN, is a strength coach, powerlifter, natural bodybuilder, and is the guy in the trenches doing all the research that we love to read! Eric has some interesting research studies planned that pertain directly to bodybuilders so be sure to follow him at @EricTrexler
LEARN MORE ABOUT THE HOSTS
ABOUT ALEX KIKEL, Prep Coach
MS, PES, NASM CPT, NASE Speed and Explosion Specialist lvl II
Owner of The Prep Coach: Online Prep Coaching Service (www.theprepcoach.com)
http://www.facebook.com/alex.kikel.9
Workout Log: http://forum.bodybuilding.com/showthread.php?t=168793973
Instagram: alex_kikel
Email: alex@theprepcoach.com
Amateur Bodybuilder & RAW Powerlifter
ABOUT AUSTIN STOUT, Prep Coach
Founder and CEO of Integrated Muscle and Health
Gym Owner
B.S. Nutrition Science
CPT
Certified Strength and Conditioning Coach
Facebook: Austin.stout.12
IG: Austinst8
•••SUPPORT OUR SPONSOR•••
(SITE ENHANCEMENT OIL) www.mediphorm.com___use discount code “BFR” for 10% off your order!
(SUPPLEMENTS) www.projectad.me___use discount code “BFR25” for 25% off your order!
•••FIND THE EPISODES•••
https://itunes.apple.com/us/podcast/beastfitness-radios-podcast/id1065532968
www.youtube.com/user/NaturallyGreatBB
http://beastfitnessradio.libsyn.com